OCT Eccentric Fixation and Amblyopia in Children

This study is looking at how two treatments affect "lazy eye" (amblyopia) in children aged 4 to 16. Researchers want to understand the relationship between how the eye fixes on objects (OCT eccentric fixation), eye movements, and how well the eye sees in children with amblyopia. The study will test standard amblyopia treatment (an eye patch) and a common training method called After-image and MIT trainer. To join, your child must have amblyopia with vision of 20/40 or worse in the affected eye, and the vision difference between eyes must be at least two lines on an eye chart. The main goal is to see how OCT eccentric fixation changes after 12 weeks of treatment. The study plans to enroll 30 children, but its current status is unclear.

Study design: This interventional study plans to enroll 30 participants. It is not specified if it is randomized or blinded.
What's involved: Participants will receive either an eye patch or After-image and MIT trainer. Changes in OCT eccentric fixation will be measured at 12 weeks.
Compensation: Not stated in the trial record.
Follow-up: Participants will be followed for at least 12 weeks after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

OCT Eccentric Fixation and Amblyopia in Children

UNKNOWN

NAAges 4–16InterventionalTreatment

State University of New York College of Optometry

~30 participants

Updated 2024-04-23 on ClinicalTrials.gov

What's tested:eye patchAfter-image and MIT trainer

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

OCT eccentric fixation

Measured over 12 weeks

Conditions

Amblyopia

Where it's being run

1 sites across 1 states

New York1

Study leadership

Jingyun Wang · PRINCIPAL_INVESTIGATOR · SUNY College of Optmetry

Who to contact

Jingyun Wang, PhD

[email protected]

2129385759

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D;

strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery;

combined type included those who meet the criteria of both anisometropia and strabismus.

For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old.

For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.

Exclusion

born before 32 weeks gestational age;

neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;

congenital or acquired macular pathology.

What this trial measures

OCT eccentric fixation12 weeks
eccentric fixation measured with OCT imaging.

Trialytics