Observational Study on Pain After Limb Amputation

This study is looking at how different medical treatments and procedures affect pain after a limb amputation. Doctors want to understand which therapies, like nerve blocks or epidurals, work best to manage pain, including phantom limb pain (feeling pain in a limb that is no longer there) and pain in the remaining limb. They will track your pain levels at rest and during movement using a 0-10 scale at several points over one year after your surgery. This will help them learn if certain treatments given at specific times (before or after amputation) lead to better long-term pain relief. You can join if you are between 18 and 89 years old and are scheduled for a limb amputation at Penn State Hershey Medical Center.

Study design
This is an observational study involving up to 350 participants. It aims to collect information about existing treatments rather than testing a new one.
What's involved
You would have your pain severity assessed on post-operative day 1, day 7, 30 days, 90 days, 6 months, and 1 year after surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after their amputation surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05716321

Pain and Disability Outcomes in Post Amputation Patients

Recruiting
Not specifiedAges 18–89Observational
Milton S. Hershey Medical Center
~350 participants
Updated 2026-05-07 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Pain Severity at rest and movement
Measured over 1 year
Limb Pain, Phantom
Residual Limbs Pain
Disability Physical

NCT05716321

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Penn State Health Milton S. Hershey Medical Center

    Hershey, Pennsylvaniano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Sanjib Adhikary, M.B.B.S., MD · PRINCIPAL_INVESTIGATOR · Milton S. Hershey Medical Center

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  • Change in Pain Severity at rest and movement1 year

    The primary outcome will be assessment of pain severity at rest and with movement as measured by pain scores on Numerical Rating Scale (NRS) 0 to 10 taken on post-operative day 1, day 7, 30 days, 90 days, 6 months, and 1 year (+/- 3 days at each time point). 0 means no pain and 10 means the worst pain ever.