Metabolic Effects of Intermittent Fasting Study
This study is looking at how intermittent fasting affects your body's metabolism, especially if you are at high risk for diabetes. Researchers want to see if the benefits of fasting, like changes in fat levels and bone health, happen even if you don't lose weight. You might be able to join if you are between 21 and 45 years old, have a BMI (Body Mass Index) between 21 and 29, have normal thyroid function, and have a close relative with type 2 diabetes or a history of gestational diabetes. The study will measure changes in fat content and bone structure over three months to understand these effects. The current status of this study is unclear, and it plans to enroll 90 participants.
- Study design
- This is an interventional study planning to enroll 90 participants. It compares a fasting group to a group focused on maintaining their current weight.
- What's involved
- Participants will either fast one day per week for 12 weeks or receive counseling to maintain their body weight and on optimal diet and activity. Measurements will be taken at the beginning of the study and after 3 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 3 months, with measurements taken at baseline and at the 3-month mark.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Metabolic Effects of Intermittent Fasting
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Pouneh Fazeli, MD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Triglyceride carbon content and degree of saturationBaseline, 3 months
Change in triglyceride carbon content and degree of saturation (% variation explained by both carbon number and double bond number in a regression model) between Baseline and Final Intervention visits
- Trabecular bone microarchitectureBaseline, 3 months
Change in trabecular bone volume fraction at the radius between Baseline and Final Intervention visits