Low Glycemic Load Diet for Cystic Fibrosis-Related Diabetes
This study is looking at how a low glycemic load (LGL) diet affects adults with cystic fibrosis-related diabetes (CFRD). The LGL diet aims to help manage blood sugar levels and improve body composition. For 8 weeks, you would receive meals from a food delivery service that follow the LGL diet. After that, you would follow the LGL diet on your own for 4 months with support from a nutritionist. Researchers will use continuous glucose monitors (CGM) to see how your blood sugar levels change. They will also look at your insulin needs, body composition (how much fat and muscle you have), and quality of life. You can join if you are 18 to 70 years old, have cystic fibrosis (CF) with pancreatic insufficiency, and meet certain criteria for CFRD, such as a recent high blood sugar test or A1c level. The study aims to see if this diet helps keep your blood sugar in a healthy range.
- Study design
- This is an interventional study with 15 participants. It tests a low glycemic load diet in a controlled setting and then in everyday life.
- What's involved
- You would follow a low glycemic load diet for 8 weeks with delivered meals, then for 4 months on your own with nutritionist support. Your blood sugar will be monitored at the start, after 8 weeks, and after 4 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants are followed for 4 months after the initial 8-week meal delivery phase to assess long-term effects.
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The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Kevin J Scully, MB BCh BAO · PRINCIPAL_INVESTIGATOR · Rhode Island Hospital
- Melissa S Putman, MD, MSc · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in percent time in target range 70-180 mg/dLBaseline, post-meal delivery phase (8 weeks), post-free-living conditions phase (4 months)
Continuous glucose monitoring