vGRID SBRT for Unresectable or Metastatic Liver Cancer
This study is testing a new way to deliver radiation therapy called vGRID SBRT (Stereotactic Body Radiation Treatment) for people with liver cancer (hepatocellular carcinoma or mixed HCC and cholangiocarcinoma) that cannot be removed by surgery or has spread. The goal is to find the highest safe dose of this radiation treatment. You may be able to join if you are 18 or older, have a good performance status (meaning you can perform daily activities), and have confirmed liver cancer. The study will look at how well people tolerate the treatment and any side effects. The current status of the study is unclear, and it plans to enroll 18 participants.
- Study design
- This is an interventional study with a planned enrollment of 18 participants. It is designed to find the maximum tolerated dose of a single radiation treatment.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, maximum tolerated dose, is measured from the first day after treatment through 3 months post-radiation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
vGRID SBRT: A Phase I Clinical Trial in Unresectable or Metastatic HCC
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- David Akhavan, MD · PRINCIPAL_INVESTIGATOR · University of Kansas Medical Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Maximum tolerated dose (MTD) of Single Fraction GRID SBRTFirst day of post-GRID SBRT through 3 month post-radiation
Safely identify MTD of Single Fraction GRID SBRT and CTCAE v5.0 related toxicity: Irreversible grade 3 hepatotoxicity, grade 4 or 5 hepatotoxicity, grade 4 or 5 gastrointestinal toxicity.