Observational Study for Sinonasal, Nasopharyngeal, and Skull Base Tumor Survivors

This study aims to understand the symptoms and changes experienced by people treated for sinonasal (nose and sinus), nasopharyngeal (upper throat behind the nose), and skull base tumors. Researchers will assess how well patients are functioning and the types of symptoms they have, including pituitary hormone levels, hearing, vision, and speech. The study is looking for 300 participants aged 18 or older who have been diagnosed with or are suspected of having these types of tumors and plan to receive most of their treatment at MD Anderson Cancer Center. The main goal is to measure symptom burden using a specific questionnaire (MD Anderson Symptom Inventory Head and Neck Module) over about one year to see what success looks like for patients.

Study design
This is an observational study, meaning researchers will collect information without providing new treatments. It plans to enroll 300 participants.
What's involved
Participants will undergo standard of care assessments, including lab draws, hearing tests, eye exams, teeth and jaw exams, and speech and swallowing evaluations.
Compensation
Not stated in the trial record.
Follow-up
Symptoms will be measured through study completion, which is an average of one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05733091

Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~300 participants
Updated 2026-04-21 on ClinicalTrials.gov
What's tested:Standard of Care

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
MD Anderson Symptom Inventory Head and Neck Module (MDASI-HN)
Measured over through study completion; an average of 1 year
Tumors

NCT05733091

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • M D Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Shirley Su, MBBS · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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  • MD Anderson Symptom Inventory Head and Neck Module (MDASI-HN)through study completion; an average of 1 year

    MD Anderson Symptom Inventory Head and Neck Module (MDASI-HN) is a disease specific PRO instrument validated for patients with head and neck cancer. It is the most commonly utilized instrument in the head and neck cancer population, of which sinonasal and nasopharyngeal tumors are disease subsites. Score scale from 0 (symptom has been present) to 10 (the symptom was as bad as you can imagine it could be)