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I-CARE 2: Mobile Telehealth for Alzheimer's Caregivers

This study is looking at how a mobile app called Brain CareNotes can help unpaid caregivers of people with Alzheimer's disease or related dementias (ADRD). The app aims to reduce the burden caregivers feel and lessen the behavioral and psychological symptoms (BPSD) their loved ones experience. You might be able to join if you are an unpaid caregiver for someone with ADRD, live in the community, and speak English. The study will compare Brain CareNotes to another app, Dementia Guide Expert, which provides education only. Researchers will measure caregiver burden and patient BPSD after 12 months to see if Brain CareNotes is helpful. This study plans to enroll 184 caregivers, but its current status is unclear.

Study design
This is a randomized, controlled study involving 184 caregivers. Participants will be assigned by chance to use either the Brain CareNotes app or an education-only app for 12 months.
What's involved
You would use a mobile app for 12 months, with reminders. Researchers will collect information from you at the start, at six months, and at 12 months.
Compensation
Not stated in the trial record.
Follow-up
Your caregiver burden and the patient's symptoms will be measured at 12 months.

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NCT05733520

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms

Recruiting
NAAges 18+InterventionalSupportive care
Indiana University
~184 participants
Updated 2025-11-24 on ClinicalTrials.gov
What's tested:Brain CareNotesDementia Guide Expert

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Caregiver Burden
Measured over 12 months
+1 more outcome measured

Conditions

Caregiver Burden
Alzheimer Disease

Explore related trials

Alzheimer's DiseaseDementia

Where it's being run

2 sites across 1 states
Indiana2

Study leadership

  • Richard J Holden, PhD · PRINCIPAL_INVESTIGATOR · Indiana University
  • Malaz Boustani, MD · PRINCIPAL_INVESTIGATOR · Indiana University

Who to contact

Miriam J Rodriguez, PhD
[email protected]
(812) 856-1661
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Self-identified primary unpaid caregiver of a person diagnosed with ADRD (at any stage) who are:
Receiving primary care and
Community-dwelling;
English literate;
Age ≥ 18 years

Exclusion

Care recipient is a permanent resident of an extended care facility (nursing home);
Involvement in another clinical trial that would prevent or interfere with study objectives;
Sensory or other impairment prohibiting the use of a mobile touchscreen device or other study activity (after correction)

What this trial measures

  • Caregiver Burden12 months

    The burden experienced by caregivers caused by their caregiving responsibilities measured by the Neuropsychiatric Inventory (NPI) caregiver distress sub-score. The distress score is calculated by adding the distress score for each of the 12 items of the NPI. A score of 0 would indicate that the BPSD cause no distress while a score of 60 would indicate that each symptom causes severe distress for the caregiver.

  • Patient BPSD12 months

    Behavioral (e.g. agitation, aggression, wandering) and psychological (e.g. delusions, hallucinations) symptoms of dementia as measured by the Neuropsychiatric Inventory (NPI). The NPI is a 12-item questionnaire. The total score is calculated by adding the product of the frequency and severity of those 12 items. A score of 0 would indicate that no symptoms are present while a score of 144 would indicate that all symptoms are present at the highest level of frequency and severity.