NCT05736406
A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma
Active, Not Recruiting
PHASE1Ages 18–75InterventionalTreatmentHemerion Therapeutics
~12 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 200 J/cm^25-ALA HCl intraoperative Photodynamic Therapy (PDT) at 400 J/cm^2
At a glance
Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Maximal Tolerated Dose (MDT) of light for Photodynamic Therapy
Measured over 4 weeks after intervention
Conditions
Where it's being run
2 sites across 2 statesPennsylvania1
France1
Study leadership
- Jan Drappatz, MD · PRINCIPAL_INVESTIGATOR · UPMC Presbyterian Shadyside Hospital, Pittsburgh, PA
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Maximal Tolerated Dose (MDT) of light for Photodynamic Therapy4 weeks after intervention
Evaluation of Dose Limiting Toxicities (DLT) to define MDT