Second Window Indocyanine Green for All Nervous System Tumors
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Tumor NIR Signal Compared to Background Brain Normal Signal (SBR)Surgery
SBR analysis will be stratified by histology, and the dosing and timing flowchart will be used to achieve optimal SBR.
- NIR EfficiencySurgery
After examining the "equivocal tissue" with white light and NIR imaging, a per person success will be recorded, if least one additional specimen is resected using NIR. NIR will be considered efficacious, if significantly more than 10% of patients meet the success criteria. Each histology will be tested separately.
- NIR True Positive RateSurgery
Of the additionally resected specimens using NIR, we will find the true positive rate based on pathology. The entire sample will be evaluated jointly; then, each histology will be evaluated separately as there may be multiple specimens per patient surgery. NIR will be considered efficacious if the true positive rate is significantly greater than 50%.