Back to search results
NCT05746247

Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

Completed
NAAges 18+InterventionalDiagnostic
University of Pennsylvania
~610 participants
Updated 2026-08-20 on ClinicalTrials.gov
What's tested:Testing centralized referral mechanism for PCPsInviting patients to complete a telehealth appointment with a lipid specialist for an FH evaluation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of flagged patients diagnosed with FH (familial hypercholesterolemia) as a result of the intervention
Measured over Day 1 - post intervention study visit

Conditions

Familial Hypercholesterolemia

Explore related trials

Hyperlipoproteinemia, Type IIa

NCT05746247

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Pennsylvania Health System

    Philadelphia, Pennsylvaniano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Must be a patient at Penn Medicine
Must have been flagged by the FIND FH tool as having a high probability of FH
First language is English
Resides in PA or NJ

Exclusion

Already have been clinically diagnosed with FH using the proper ICD-10 code
Currently see a lipid specialist at Penn Medicine
Pass study clinician's Study Validity Check

What this trial measures

  • Proportion of flagged patients diagnosed with FH (familial hypercholesterolemia) as a result of the interventionDay 1 - post intervention study visit

    Patients will be evaluated for familial hypercholesterolemia (FH), an underdiagnosed genetic type of high cholesterol. An FH diagnosis will be defined using the Dutch Lipid Clinic Network Diagnostic (DLCN) Criteria for FH (Unlikely, Possible, Probable, Definite). The clinician will also make a clinical assessment of FH informed by the DLCN score and clinical expertise from the appointment.