Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

This study is looking at a new way to manage pain for people with multiple rib fractures. It compares a procedure called a Serratus Anterior Plane Block (SAPB), which uses an ultrasound to guide a local anesthetic (Bupivacaine) to the affected area, against standard pain medications given by IV, injection, or mouth. The study wants to see if SAPB can reduce pain, improve breathing, and potentially lower the amount of other pain medications needed. You might be able to join if you are over 18, have more than one rib fracture diagnosed by X-ray or CT scan, and need pain medicine for your ribs in the emergency department. The main goal is to see how much pain people have two hours after treatment.

Study design
This is a randomized controlled trial, meaning participants are randomly assigned to receive either the SAPB procedure or standard pain medications. The study plans to enroll 60 participants.
What's involved
You would receive either the SAPB procedure or standard pain medications. Your pain levels would be measured at 2 hours.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint for pain is measured at 2 hours after treatment.

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NCT05748366

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

Recruiting
NAAges 18+InterventionalTreatment
WellSpan Health
~60 participants
Updated 2025-07-18 on ClinicalTrials.gov
What's tested:Serratus Anterior Plane Block (SAPB)Standard Analgesic Medications

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual Analog Pain Score (VAS) at 2 hours
Measured over 2 hours
Rib Fracture Multiple
1 sites across 1 states
Pennsylvania1
  • Daniel Kreider, MD · PRINCIPAL_INVESTIGATOR · WellSpan Health

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Eligibility criteria

Inclusion

Age \>18 years
\>1 Unilateral, acute rib fractures diagnosed on x-ray or CT imaging
Patient presenting to the WellSpan York Hospital ED
Patient requiring IV analgesia or oral opioid to control pain related to rib fractures

Exclusion

Age \<18 years
Inability to provide informed consent
Allergy to local anesthesia
Subsequent visit for rib fractures
Patients taken emergently to the OR or discharged from the ED
Significant distracting injuries/polytrauma that would not be expected to be responsive to analgesia from SAPB and confound pain scores, i.e. long bone fractures, intraabdominal injuries, etc.
  • Visual Analog Pain Score (VAS) at 2 hours2 hours

    Change in pain score on a visual analog scale (VAS) at 2 hours following randomization to ultrasound guided SAPB or analgesic medication only.