This study is looking for the best way to manage pain and sedation for trauma patients who need a breathing machine (mechanical ventilator). Currently, many patients receive continuous drips of pain medicine and sedatives, with a daily break to check their brain function. This study compares that approach to a new strategy called "Analgesia First Sedation." In this new strategy, pain is treated first with occasional doses of pain medicine, and sedatives are only used for short periods if you become agitated. The goal is to see if the Analgesia First Sedation strategy can reduce the number of days you need to be on a breathing machine. You might be able to join if you are at least 18 years old, on a breathing machine for at least 48 hours, and are a candidate for weaning off the machine. The study plans to enroll 170 participants, but its current recruitment status is unclear.

Study design

This is an interventional study comparing two different sedation strategies in approximately 170 mechanically ventilated trauma patients.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, mechanical ventilation days until successful extubation, will be measured at 28 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.