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Observational Study on Blood Pressure Variability After Stroke

This study is looking at how changes in blood pressure (blood pressure variability) affect people who have had an acute ischemic stroke (a stroke caused by a blood clot). Researchers want to understand if these blood pressure changes are linked to how well patients recover and if there are ways to reduce these changes. You might be able to join if you are 18 or older and have had an ischemic stroke in a specific part of your brain. The study will follow participants for up to one year to see how their functional recovery and brain imaging change over time. This is an observational study, meaning no specific interventions are being tested.

Study design
This is an observational study involving 150 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your functional outcome will be measured at 90 days and 1 year, and imaging outcome will be measured around 72 hours after the stroke.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05756257

Blood Pressure Variability and Ischemic Stroke Outcome

Recruiting
Not specifiedAges 18+Observational
Yale University
~150 participants
Updated 2026-05-20 on ClinicalTrials.gov

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Functional outcome
Measured over 90 days and 1 Year
+1 more outcome measured

Conditions

Acute Ischemic Stroke
Blood Pressure Variability

Explore related trials

Ischemic Stroke

Where it's being run

3 sites across 3 states
Connecticut1
Illinois1
Massachusetts1

Study leadership

  • Adam de Havenon, MD · PRINCIPAL_INVESTIGATOR · Yale University

Who to contact

Adam de Havenon, MD
[email protected]
203-785-4085
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Ischemic stroke according to the American Heart Association (AHA) definition and either:

Exclusion

Pre-morbid mRS ≥3
Predicted hospital system admission \<72 hours
Pacemaker or other MRI contraindications per American College of Radiology guidelines

What this trial measures

  • Change in Functional outcome90 days and 1 Year

    Modified Rankin Scale, the scale uses a range of 0-6 where higher scores indicate decreased function.

  • Imaging outcome72 hours +/- 60 hours

    Final infarct volume on MRI at 72 hours