CT TAVR Abdomen Study: Reduced Contrast for Imaging

This study is looking at a new way to perform CT scans for people who need a TAVR (Transcatheter Aortic Valve Replacement) procedure. Researchers are testing if using a lower dose of Omnipaque, an iodinated contrast agent, with a special type of CT scanner called Dual Energy CT, can still provide clear images. This is important because there have been shortages of contrast agents, and using less might also reduce the risk of kidney problems. The study aims to see if these lower-dose images are good enough for planning your TAVR procedure. You can join if you are between 18 and 88 years old and are scheduled for a TAVR abdominal CT scan. The study will measure the quality of the images over 18-24 months.

Study design
This interventional study plans to enroll 164 participants. It is testing a reduced dosage of Omnipaque with a Dual Energy CT device.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The diagnostic quality of images will be measured at 18-24 months after the scan.

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NCT05758701

CT TAVR Abdomen Study

Recruiting
PHASE4Ages 18–88InterventionalDiagnostic
University of Maryland, Baltimore
~164 participants
Updated 2026-07-01 on ClinicalTrials.gov
What's tested:Iodinated Contrast Agent (Omnipaque)Dual Energy CT

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Diagnostic Quality of Images
Measured over 18-24 months
Transcatheter Aortic Valve Replacement
1 sites across 1 states
Maryland1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

scheduled to receive TAVR abdominal CT

Exclusion

cannot undergo CT scan
Allergy to intravenous contrast not controlled by steroids or benadryl
GFR\<30
  • Diagnostic Quality of Images18-24 months

    5-point Likert Scale