OCT Vibrography for Measuring Tissue Properties

This study is testing a new device called OCT vibrography to measure the stiffness of human tissues like the cornea (the clear front part of your eye) and skin. Researchers want to see if this device can help them better understand and diagnose conditions like keratoconus (a thinning of the cornea), skin diseases, and gum diseases. You may be able to join if you are between 18 and 75 years old and have healthy eyes. The main goal is to see how many people can successfully complete the OCT vibrography without any serious unexpected problems related to the device. The study is currently recruiting participants.

Study design
This is an interventional study planning to enroll 90 participants. It is not specified if the study is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year to monitor for any adverse events related to the device.

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NCT05759780

OCT Vibrography for Biomechanical Properties of Tissues

Recruiting
NAAges 18–75InterventionalBasic science
Massachusetts General Hospital
~90 participants
Updated 2026-08-19 on ClinicalTrials.gov
What's tested:Optical imaging of the tissues

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of subjects to successfully complete OCT Vibrography without serious unanticipated adverse events related to application of the device.
Measured over 1 year
Cornea
Skin Diseases
Gingival Diseases
1 sites across 1 states
Massachusetts1
  • Seok-Hyun Yun, PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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Eligibility criteria

Exclusion

Subjects with history of eye diseases, and previous eye surgeries.
Subjects with diabetes, glaucoma family history
Subjects allergic to anesthetic eyedrop, especially proparacaine
Subjects with severe allergy
Subjects who have difficulty biting
Subjects who have recurrent corneal erosion
  • Number of subjects to successfully complete OCT Vibrography without serious unanticipated adverse events related to application of the device.1 year

    Frequency and severity of all treatment-related adverse events