Chronic Postsurgical Pain in Children with Cerebral Palsy

This study is observing children aged 5 to 17 years old with Cerebral Palsy (CP) who are having lower extremity or spine orthopedic surgery. The goal is to understand the pain they experience before and after surgery, and to find out what factors might lead to chronic postsurgical pain (pain that lasts a long time after surgery). Researchers will track changes in pain using a tool called the Brief Pain Inventory (BPI) from one week before surgery up to 12 months after surgery. This information will help doctors better predict and manage pain for children with CP undergoing these surgeries. There are 500 participants planned for this study.

Study design
This is an observational study, meaning researchers will watch and collect information without providing any specific interventions. It plans to include 500 participants.
What's involved
You would complete questionnaires and surveys via email and text message. You would also have in-person sensory tests and in-person gait and motion analysis.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after surgery.

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NCT05764681

Chronic Postsurgical Pain

Recruiting
Not specifiedAges 5–17Observational
Chantel Burkitt
~500 participants
Updated 2025-09-19 on ClinicalTrials.gov

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Brief Pain Inventory (BPI) score from 1 week preoperative to 1, 3, 6, and 12 months postoperative
Measured over 1 month preoperative, and 1, 3, 6, and 12 months postoperative
Cerebral Palsy
Chronic Post Surgical Pain
2 sites across 2 states
Delaware1
Minnesota1
  • Chantel Burkitt, PhD · PRINCIPAL_INVESTIGATOR · Gillette Children's, University of Minnesota

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Eligibility criteria

Inclusion

CP diagnosis
Have a scheduled lower extremity or spine orthopedic surgery

Exclusion

Non-English speaking and reading parent/guardian
  • Change in Brief Pain Inventory (BPI) score from 1 week preoperative to 1, 3, 6, and 12 months postoperative1 month preoperative, and 1, 3, 6, and 12 months postoperative

    The BPI assesses pain location, pain intensity at worst, least, average, and right now as well as the degree to which pain interferes with activities of daily living (e.g., sleep, relationships, and mobility). Items are scored on an 11-point scale (0 = does not interfere, 10 = completely interferes) creating a total interference score ranging from 0-120 (higher scores mean more pain interference). The BPI has been adapted for and tested with individuals with severe CP, resulting in excellent internal consistency (Cronbach's alpha = 0.89) and validity evidence \[1, 29, 30\]. The BPI will take parents/children 1-2 minutes to complete.