Investigating Smoking Cessation Interventions in Rural Primary Care

This study is looking into new ways to help people quit smoking in rural primary care clinics. It compares two approaches: an electronic visit (e-visit) for smoking cessation, and "treatment as usual" which involves information about quitting and contacting your doctor. The e-visit is like an online questionnaire about your smoking habits and preferences for quitting medications. You might get a prescription for a smoking cessation medication if you're in the e-visit group, but you don't have to take it. The study aims to see how well these interventions help people stop smoking at 1, 3, and 6 months. To join, you need to smoke at least one cigarette a day, be 18 or older, and use or be willing to enroll in Epic's MyChart program with a valid email and a smartphone. The study is currently unclear on its recruitment status and plans to enroll 288 participants.

Study design
This is an interventional study where participants will be randomly assigned to receive either the smoking cessation e-visit or treatment as usual. It plans to enroll 288 participants.
What's involved
You would complete questionnaires and provide breath samples at four different times over about 24 weeks. You would also need to have a valid email and a smartphone to access study assessments and MyChart messages.
Compensation
Not stated in the trial record.
Follow-up
The study will measure smoking cessation at 1, 3, and 6 months after starting the intervention.

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NCT05764759

Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

Recruiting
NAAges 18+InterventionalHealth services
Medical University of South Carolina
~288 participants
Updated 2026-03-05 on ClinicalTrials.gov
What's tested:Smoking cessation e-visitTreatment as usual

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Smoking Cessation
Measured over Month 1
+5 more outcomes measured
Smoking Cessation
1 sites across 1 states
South Carolina1

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Eligibility criteria

Inclusion

Current cigarette smoking, defined as smoking 1+ cigarettes per day, for 20+ days out of the last 30, for the last 6+ months
Age 18+
Enrolled in Epic's MyChart program or willing to enroll
Possess a valid e-mail address that is checked daily to access study assessments and MyChart messages
Owner of an iOS or Android compatible smartphone to provide remote CO readings
Have a valid address at which mail can be received (for mailing iCO™)
English fluency
  • Smoking CessationMonth 1

    Self-reported smoking via Timeline Follow Back will be biochemically verified via breath CO, with abstinence defined as CO of ≤ 4 ppm. Self-report and CO data will be utilized together to determine 7-day PPA.

  • Smoking CessationMonth 3

    Self-reported smoking via Timeline Follow Back will be biochemically verified via breath CO, with abstinence defined as CO of ≤ 4 ppm. Self-report and CO data will be utilized together to determine 7-day PPA.

  • Smoking CessationMonth 6

    Self-reported smoking via Timeline Follow Back will be biochemically verified via breath CO, with abstinence defined as CO of ≤ 4 ppm. Self-report and CO data will be utilized together to determine 7-day PPA.

  • Reduction in Cigarettes Per DayMonth 1

    Reduction in cigarettes per day of 50% via self-report timeline follow back assessment.

  • Reduction in Cigarettes Per DayMonth 3

    Reduction in cigarettes per day of 50% via self-report timeline follow back assessment.

  • Reduction in Cigarettes Per DayMonth 6

    Reduction in cigarettes per day of 50% via self-report timeline follow back assessment.