Diet Interventions for Knee Osteoarthritis Pain

This study is exploring if a specific diet can help reduce pain for people with knee osteoarthritis (OA). Researchers are looking at how a 6-week randomized diet affects pain levels. They will measure pain using standard scales like the Western Ontario and McMaster Osteoarthritis Index (WOMAC) and the Brief Pain Inventory (BPI) at several points over nine weeks. You might be able to join if you are between 40 and 75 years old, have a diagnosis of knee OA with pain most days, and meet certain dietary and health criteria. The study aims to enroll 200 participants to understand if diet can be a helpful, non-medication option for pain relief.

Study design
This is an interventional study, meaning participants will receive a specific diet. It is a randomized study, and 200 adults with knee osteoarthritis will be enrolled.
What's involved
You will undergo a telephone screening and a screening interview to assess your OA status, diet, and health history. The diet intervention itself lasts for 6 weeks, with pain measurements taken at several points over nine weeks.
Compensation
Not stated in the trial record.
Follow-up
Pain levels will be measured at baseline, before the intervention (week 3), during the intervention (week 6), and immediately after the intervention (week 9).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05785884

Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain

Recruiting
NAAges 40–75InterventionalTreatment
University of Alabama at Birmingham
~200 participants
Updated 2026-08-12 on ClinicalTrials.gov
What's tested:Diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Western Ontario and McMaster Osteoarthritis Index pain change
Measured over Baseline (week 0), immediately before the intervention (week 3), 3 weeks after initiating the intervention (week 6), immediately after the intervention (week 9)
+2 more outcomes measured
Knee Osteoarthritis

NCT05785884

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Alabama at Birmingham

    Birmingham, Alabamastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Robert E Sorge, PhD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

Opens a ready-to-send draft in your own email app — review before sending.

  • Western Ontario and McMaster Osteoarthritis Index pain changeBaseline (week 0), immediately before the intervention (week 3), 3 weeks after initiating the intervention (week 6), immediately after the intervention (week 9)

    The Western Ontario and McMaster Osteoarthritis Index (WOMAC) pain score is a 0-20 score with higher scores reflecting more severe pain. Questions 1-5 are summed to provide a WOMAC pain score. Change scores will be calculated. Greater change scores would reflect more improvement.

  • BPI pain changeBaseline (week 0), immediately before the intervention (week 3), 3 weeks after initiating the intervention (week 6), immediately after the intervention (week 9)

    The Brief Pain Inventory (BPI) pain score is a 0-40 score with higher scores reflecting more pain. Questions 3-6 are scored on 0-10 and are summed to provide an overall pain score. Change scores will be calculated.

  • TUG pain intensity changeBaseline (week 0), immediately before the intervention (week 3), 3 weeks after initiating the intervention (week 6), immediately after the intervention (week 9)

    Before and after the Timed-Up-And-Go (TUG) task, participants will be asked to rate the intensity of pain in their knee on a 0-100 scale. The difference in the ratings will be considered the evoked pain score. Change scores will be calculated.