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Opioid Tapering Before Total Joint Replacement

This study is developing a program to help people reduce their opioid (pain medication) use before total knee or hip replacement surgery. If you're planning one of these surgeries in the next 4-8 weeks, are currently taking a stable dose of oral opioids, and speak English, you might be able to join. The main goals are to see if this program is practical and acceptable to patients, and if it helps lower opioid doses before surgery. You'll work with a pharmacist who will help you create a plan to gradually reduce your opioid dose, and they will check in with you weekly by phone until your surgery.

Study design
This is an interventional study planning to enroll 45 participants. It is not specified if it is randomized or blinded.
What's involved
You will meet with a clinical pharmacist and have weekly phone follow-ups until your surgery, which is planned for 4-8 weeks after enrollment.
Compensation
Not stated in the trial record.
Follow-up
Your acceptability of the intervention will be measured until approximately 2 weeks after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05788016

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Recruiting
NAAges 18+InterventionalSupportive care
University of Alabama at Birmingham
~45 participants
Updated 2026-05-29 on ClinicalTrials.gov
What's tested:opioid taper

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Acceptability
Measured over From enrollment until approximately 2 weeks after surgery

Conditions

Arthritis Knee
Arthritis Hip
Chronic Pain

Explore related trials

Arthritis

Where it's being run

1 sites across 1 states
Alabama1

Study leadership

  • Kevin R Riggs, MD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

Who to contact

Kevin R Riggs, MD
[email protected]
205-934-0778
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks
currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months
have a reliable telephone number for contact
speaks English

Exclusion

Taking opioid medications that include:
Buprenorphine
Methadone
Long-acting formulations of opioid pain medications (e.g., extended-release oxycodone and extended-release morphine)
Transdermal formations of opioid pain medications (e.g., fentanyl patches)

What this trial measures

  • AcceptabilityFrom enrollment until approximately 2 weeks after surgery

    Mixed-methods assessment of the intervention by participants. Participants will provide qualitative feedback at multiple points during and after the intervention, and will quantitatively rate satisfaction at the end of the study. These results will be analyzed jointly to determine acceptability.