Improving Timely Treatment for Head and Neck Cancer

This study is for people with head and neck cancer, including oral cavity, oropharynx, and larynx cancers. It compares two approaches to help patients get timely postoperative radiation therapy (PORT), which is radiation treatment after surgery. One approach is called ENDURE, which offers patient education and support to connect you with community resources. The other approach is "treatment as usual," which is standard care. The study wants to see if ENDURE helps patients start their PORT sooner. You may be able to join if you are 18 or older and have certain types and stages of head and neck squamous cell carcinoma. The study is currently unclear on its recruitment status and plans to enroll 532 participants.

Study design
This study is a stepped-wedge cluster randomized trial, meaning groups of cancer centers will switch from standard care to the ENDURE program over time. It plans to include 532 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main goal is measured at 3 months, looking at when timely postoperative radiation therapy (PORT) is started.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05793151

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

Recruiting
NAAges 18+InterventionalHealth services
Medical University of South Carolina
~532 participants
Updated 2025-12-11 on ClinicalTrials.gov
What's tested:ENDURE

At a glance

Recruiting sites
4 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Initiation of Timely PORT
Measured over 3 months
Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Oropharynx Cancer
Oral Cavity Cancer
Larynx Cancer
4 sites across 4 states
Missouri1
North Carolina1
South Carolina1
Texas1
  • Evan M Graboyes, MD, MPH · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

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  • Initiation of Timely PORT3 months

    The initiation of PORT \> 6 weeks (42 days) following definitive surgery for HNSCC.