This study is looking into the role of genetic differences in conditions like sickle cell disease (SCD) and thalassemia. Researchers want to understand how these genetic differences affect how severe the disease is. You might be able to join if you have a clinical diagnosis of an inherited hemoglobinopathy, such as sickle cell disease or thalassemia, and are at least 2 years old. The study involves collecting a blood sample for genetic testing (GWAS). The main goal is to find new genetic factors that influence these conditions, which will be measured over 5 years. The current status of the study is unclear, and it aims to include 30,000 participants.

Study design

This is an observational study that plans to enroll 30,000 participants. It will use genetic testing (GWAS) to look at the genetic profiles of individuals with hemoglobinopathies.

What's involved

You would provide a blood sample during a routine clinical visit, if a DNA sample isn't already available from existing biobanks. You would also give your consent to participate.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, genetic modifiers, will be measured at 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.