Safety Study of RAD301 for Cancer and Healthy Volunteers
This study is looking at the safety of a drug called RAD301 ([68Ga]-RAD301) in healthy volunteers and people with certain cancers, including pancreatic, non-small cell lung, esophageal, cervical, endometrial, or ovarian cancer. The researchers want to see how the body handles RAD301 and how much radiation it gives off. You would receive a single dose of RAD301 through an IV (intravenous) and have scans to track it. The study will also check for any side effects over four weeks. This is an early-stage study, and the enrollment status is currently unclear.
- Study design
- This is an early-stage, open-label study involving a single dose of RAD301. It plans to enroll 9 participants, including healthy volunteers and those with specific solid tumors.
- What's involved
- You would receive a single IV dose of RAD301. You would have vital signs, ECGs (heart tests), and blood tests before and two weeks after the dose, plus three whole-body PET-CT and PET scans.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your safety and tolerability of RAD301 will be measured for four weeks after the dose.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
At a glance
Conditions
Where it's being run
2 sites across 2 statesWho to contact
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What this trial measures
- Radiation dosimetry of RAD3016 hours
Absorbed radiation dose of RAD301 in critical organs
- Radiation dosimetry of RAD3016 hours
Absorbed radiation dose of RAD301 in tumor lesions
- Safety and tolerability of RAD3014 weeks
The properties, incidence, nature and severity of AEs and SAEs per Common Terminology Criteria for Adverse Events (CTCAE) v5.0