Neuroscience-informed Treatment for Post-acute Anorexia Nervosa
This study is testing two behavioral therapies for adults recovering from Anorexia Nervosa (AN). One is called Positive Affect Treatment for Anorexia Nervosa (PAT-AN), which aims to help you find more joy in non-eating disorder activities. The other is Psychoeducational and Behavioral Therapy (PBT), a standard approach to eating disorder treatment. You might be able to join if you are 18 or older, can speak English, have been diagnosed with AN or atypical AN, and are currently in or recently discharged from higher-level care (like residential treatment). Your Body Mass Index (BMI) should be 18.5 kg/m2 or higher. The study will look at changes in your BMI and eating disorder symptoms over 24 weeks to see how well these treatments work. The current status of this study is unclear.
- Study design
- This study plans to enroll 90 participants. You will be randomly assigned to receive either PAT-AN or PBT through teletherapy.
- What's involved
- You will participate in 24 weeks of teletherapy sessions, starting within three months after discharge from higher-level care.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study measures changes from the start of treatment to the end of treatment (week 24).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Ann Haynos, PhD · PRINCIPAL_INVESTIGATOR · Principal Investigator
Who to contact
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What this trial measures
- Change in Body Mass Index (BMI) from Baseline to End of TreatmentBaseline to End of treatment (week 24)
Objective height will be captured through guided measurement at baseline. Objective weight will be measured throughout on a blind smartscale, which will transfer weight data directly to the research team by wireless internet without providing an outward display of weight to participants. Participants will have a smartscale shipped to their home. They will measure their weight at baseline and following treatment on the scale in standard street clothes (no outer garments or shoes) while on a video call with research staff.
- Change in Eating Disorder SymptomsBaseline to End of treatment (week 24)
The Eating Disorder Examination (EDE) is an investigator-based interview assessing eating disorder psychopathology that will be used as the primary measure of eating disorder symptoms. The EDE has extensive psychometric data to support its reliability and validity. The EDE comprises four subscales: Restraint, Eating Concern, Shape Concern, and Weight Concern. Each question is scored by the interviewer based on frequency over the past month from 0 (symptom not present) to 6 (symptom present every day). Each subscale score is the average of all items in the subscale, while global EDE score is the average of the four subscale scores. Higher EDE scores indicate greater severity and frequency of eating disorder symptoms.