NCT05800743

Evaluation of the GORE® Ascending Stent Graft

Enrolling by Invitation
NAAges 18+InterventionalTreatment
W.L.Gore & Associates
~370 participants
Updated 2026-05-29 on ClinicalTrials.gov
What's tested:GORE® Ascending Stent Graft (ASG device)GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device)Surgery

At a glance

Recruiting sites
0 of 41 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Primary effectiveness endpoint as measured by device technical success and absence of reintervention.
Measured over 30 Days
+1 more outcome measured
Aortic Aneurysm, Thoracic
Pseudoaneurysm
Aortic Dissection
Aorta; Lesion
41 sites across 27 states
California4
North Carolina3
Pennsylvania3
Texas3
Florida2
Michigan2
Ohio2
Virginia2
  • Eric Roselli, MD · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Chronic de novo aortic dissection with primary entry tear in the ascending aorta or arch
Chronic de novo aortic dissection with primary entry tear in the descending thoracic aorta with retrograde involvement of the aortic arch and/or ascending aorta 7. Residual aortic dissection following surgical repair of Type A aortic dissection requiring treatment (\>30 days post-surgery) 2. Anatomic compatibility with ASG device used in combination with the TBE Device based on Gore Imaging Sciences review.
  • Primary effectiveness endpoint as measured by device technical success and absence of reintervention.30 Days

    The primary effectiveness endpoint is a composite of the following events through one month post procedure: Device Technical Success and Absence of Reintervention. Technical Success is defined as including: 1. Successful access and delivery to the intended implantation site, and retrieval of the device delivery system, and; 2. Accurate placement of the device at the intended implantation site, and 3. Patency of the graft in absence of clinically significant device deformations (e.g., kinking, stent eversion, mal-deployment, misaligned deployment), and Absence of reintervention is defined as: The absence of unanticipated additional procedures related to the device, procedure, or withdrawal of the delivery system

  • Primary Safety Endpoint as measured by a composite of the absence of aortic rupture, lesion-related mortality, disabling stroke, permanent paraplegia, permanent paraparesis, and new onset renal failure requiring permanent dialysis.30 Days

    The primary safety endpoint is a composite of the following events through 30 days post endovascular procedure: * Aortic rupture * Lesion-related mortality * Disabling Stroke * Permanent paraplegia * Permanent paraparesis * New onset renal failure requiring permanent dialysis