This study is testing spironolactone, a medicine approved for high blood pressure and heart failure, to see how it works in people with Alcohol Use Disorder (AUD). Researchers want to understand how your body processes spironolactone when you also drink alcohol, and if there are any side effects. You would receive different doses of spironolactone (50 mg, 100 mg, and 200 mg per day) or a placebo (an inactive pill that looks the same). The main goal is to learn about how spironolactone and alcohol are handled by the body. This study is for people aged 21 and older who have Alcohol Use Disorder. The study is currently unclear on its status and plans to enroll 20 participants.

Study design

This is an interventional study with 20 participants, comparing spironolactone to a placebo. Participants will receive increasing doses of spironolactone or placebo in a blinded manner, meaning neither you nor the study staff will know which you are receiving.

What's involved

You will participate in three sessions, receiving increasing doses of spironolactone or placebo. During these sessions, researchers will measure how your body processes spironolactone and alcohol.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoints measure drug levels before and after oral alcohol administration, and 12 hours after oral alcohol administration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.