Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
{ "Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation for Older Adults", "This study is looking at whether combining special walking exercises with a type of brain stimulation can help older adults who are experiencing some memory or thinking problems and difficulty with movement. The study will test if a non-invasive electrical brain stimulation called Prefrontal Active tDCS (transcranial direct current stimulation) is more helpful than a \"sham\" (inactive) version of the stimulation. All participants will do walking exercises that involve complex tasks like stepping over obstacles. Researchers will measure changes in walking speed during obstacle tasks and scores on tests of executive function (a type of thinking skill) to see if the interventions are effective. You might be able to join if you are 65 or older and have experienced some decline in your thinking abilities.", "design": "This interventional study plans to enroll up to 120 older adults. It will compare Prefrontal Active tDCS with Prefrontal Sham tDCS, both combined with walking exercise.", "commitments": "You would participate in 18 sessions over a 6-week period, with each session including 30 minutes of walking and 20 minutes of tDCS. Assessments will be done at the beginning, after the 6-week intervention, and 12 weeks later.", "compensation": "Not stated in the trial record.", "follow_up": "Participants will be followed for about 12 weeks after the intervention period ends.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
At a glance
Conditions
NCT05830942
Where you'd take part
This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Brooks Rehabilitation
Jacksonville, Floridastudy coordinator listed
Recruiting
University of Florida
Gainesville, Floridastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- David J Clark, ScD · PRINCIPAL_INVESTIGATOR · University of Florida
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- walking speed for obstacle task negotiation taskbaseline, post-intervention (an average of 6 weeks after baseline), follow-up (an average of 12 weeks after post-intervention)
change in walking speed from baseline to post intervention (or follow-up) timepoint
- score on test of executive functionbaseline, post-intervention (an average of 6 weeks after baseline), follow-up (an average of 12 weeks after post-intervention)
change in score from baseline to post intervention (or follow-up) timepoint