Observational Study of Active Surveillance for Prostate Cancer

This study is looking at men with prostate cancer who are being cared for with "Active Surveillance." This means instead of immediate treatment, your cancer is closely watched. The study wants to understand how well Active Surveillance works for men with low or very low-risk prostate cancer. You could be eligible if you are a man aged 18 or older with a recent diagnosis of prostate cancer that meets certain guidelines for Active Surveillance, including very low, low, or some intermediate-risk cases. The main goal is to estimate how many men on Active Surveillance will have their cancer progress over five years. This study is currently unclear on its recruitment status.

Study design
This is an observational study planning to enroll 100 participants. It is not testing a new treatment but rather observing how patients on Active Surveillance are managed.
What's involved
Participants will complete questionnaires, have physical and rectal exams, prostate biopsies, and imaging scans (like MRIs). These visits will happen between every 6 months and every 2-3 years, depending on the specific test or procedure.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures disease progression over an average of 1 year, through study completion.

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NCT05840484

Comprehensive Monitoring of Men With Prostate Cancer Cared for by "Active Surveillance

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~100 participants
Updated 2026-08-10 on ClinicalTrials.gov
What's tested:Active Surveillance

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To estimate the 5-year disease progression rate of patients with low or very low-risk prostate cancer who choose to undergo active surveillance with remote monitoring
Measured over through study completion; an average of 1 year.
Prostate Cancer
1 sites across 1 states
Texas1
  • Christopher Logothetis, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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  • To estimate the 5-year disease progression rate of patients with low or very low-risk prostate cancer who choose to undergo active surveillance with remote monitoringthrough study completion; an average of 1 year.