Investigating PICTURE-IT and CoDeLT for Aphasia After Stroke
This study is looking at two behavioral language treatments for people who have aphasia (difficulty with language) after a stroke. The treatments are called PICTURE-IT and CoDeLT. PICTURE-IT aims to help you produce more complex language by engaging the right side of your brain. CoDeLT is a computer-based treatment that helps with naming objects. Researchers want to see if PICTURE-IT is better at improving how much you can say and how well you can describe things compared to CoDeLT. You may be able to join if you are 18 or older, speak English, and had a stroke that caused aphasia either 1-4 months ago or 6 months or more ago. The main goal is to see how much your ability to describe a picture changes after treatment, measured at baseline and one week later. The current recruitment status is unclear.
- Study design
- This is a pilot crossover study with 70 participants. The order of the two treatments (PICTURE-IT and CoDeLT) will be random, and the people assessing your progress will not know which treatment you received.
- What's involved
- You will receive two different behavioral language treatments. Your language abilities will be assessed before and immediately after each treatment, and again at 2 weeks and 2 months after both treatments. Optional saliva samples may also be collected.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your discourse will be assessed one week after treatment. Your discourse and naming abilities will also be assessed 2 weeks and 2 months after both treatments.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
At a glance
Conditions
NCT05845047
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Johns Hopkins School of Medicine
Baltimore, Marylandstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Argye E Hillis, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in discourse content as assessed by z-score for the number of meaning-carrying units used in describing a pictureBaseline, 1 week after treatment
Change in z-score for the number of meaning-carrying units used in describing a picture. There is no maximum number of meaning-carrying units, but norms are available to assist in the interpretation of this performance.