Observational Study for MACHD Registry

This observational study is looking for 50 healthy adults to help compare information for the Mayo Clinic Adult Congenital Heart Disease (MACHD) Registry. The study is not testing any specific intervention or drug. Instead, it aims to understand pulmonary vascular reserve (how well your lung blood vessels can handle changes in blood flow) at the beginning of the study. You might be able to join if you are 18 or older, have a BMI (Body Mass Index) of 30 or less, healthy blood pressure, good kidney function (eGFR > 30), and can have an MRI. We are currently unsure of the study's recruitment status.

Study design
This is an observational study aiming to enroll 50 participants. It is designed to gather information rather than test a specific treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Pulmonary vascular reserve is measured at Baseline, but no further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05849025

A Study of Invasive Hemodynamic for MACHD Registry

Recruiting
Not specifiedAges 18+Observational
Mayo Clinic
~50 participants
Updated 2026-05-05 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pulmonary vascular reserve
Measured over Baseline
Healthy
Congenital Heart Disease
1 sites across 1 states
Minnesota1
  • Alexander Egbe, MBBS, MPH · PRINCIPAL_INVESTIGATOR · Mayo Clinic
ACHD Research Program
Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Capacity to Consent
BMI \</= 30
Systolic BP \</= 140mmHg
Diastolic BP \</= 90
eGFR \> 30 (within prior 3 months) to confirm kidney function
Able to undergo an MRI

Exclusion

History of Cardiovascular disease that may affect the results of the testing performed.
Any Current orthopedic limitations
Currently taking any cardiac medication
Pregnancy
  • Pulmonary vascular reserveBaseline

    The slope of mean pulmonary artery pressure / cardiac output (mPAP/CO)