mGlide-Care for Uncontrolled High Blood Pressure in Early Alzheimer's and MCI

This study is testing a new approach called mGlide-Care to help manage high blood pressure (HTN) in people aged 60 to 85 who have early-stage Alzheimer's disease (AD/ADRD) or mild cognitive impairment (MCI). mGlide-Care uses mobile health technology to help with self-monitoring and medication management. The study aims to see if mGlide-Care is better at controlling blood pressure compared to usual care with self-monitoring support. To join, you must have uncontrolled high blood pressure, an unpaid family caregiver, and be able to speak English. You or your caregiver also need a smartphone or mobile device. The researchers will measure how well blood pressure is controlled at 6 and 12 months.

Study design
This study plans to enroll 75 participants to compare mGlide-Care with usual care plus self-monitoring support.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after starting the study.

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NCT05850416

mGlide-Care: A Partnership With Caregivers

Recruiting
NAAges 60–85InterventionalTreatment
University of Minnesota
~75 participants
Updated 2026-02-13 on ClinicalTrials.gov
What's tested:mGlide-CareUsual Care +

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
HTN control
Measured over 6 months and 12 months
HTN
1 sites across 1 states
Minnesota1

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Eligibility criteria

Inclusion

Diagnosed with early stage AD/ADRD or MCI
Have uncontrolled hypertension (HTN)
Have an unpaid, family caregiver
Have established medical diagnosis of hypertension (HTN)
English speaking
Participant or caregiver must have a smartphone or mobile device (e.g. iPad) that can transmit blood pressure (BP) from the BP monitor
Participant and caregiver capable and willing to comply with the entire study protocol
Able to give voluntary written informed consent.

Exclusion

Severe comorbid illness including end-stage kidney disease, end-stage liver disease, and life expectancy \<1 year, or if medical complexity of the patient precludes clinical trial participation
Active illicit drug use (e.g. cocaine, methamphetamines, opioids, phencyclidine) since this will interfere with HTN management
Participant and caregiver unable to complete study tasks, including are homeless, will leave the country, or will relocate in the next 12 months
Serious psychiatric illness that could interfere with treatment, assessment, or compliance including significant delusional disorders such as schizophrenia and bipolar illness
Unable or unwilling to give consent.
  • HTN control6 months and 12 months

    HTN control rates in intervention vs. control arm participants. HTN control for each participant will be defined based on personalized threshold for participant as determined by primary care.