Arginine Replacement Therapy in COVID-19
{ "Arginine Replacement Therapy for Children with COVID-19", "This study is looking at whether giving doses of Arginine Hydrochloride, a protein found naturally in the body, can improve how well cells produce energy (mitochondrial function) in children hospitalized with COVID-19. Researchers believe that severe COVID-19 can lead to a lack of arginine, which might contribute to serious complications. The study will involve 21 children, aged 3 to 21, who have COVID-19 and need hospital care. You would receive one of three different doses of Arginine Hydrochloride three times a day for up to five days, or until you are discharged from the hospital. The main goal is to see how mitochondrial function changes from the beginning of the study to day 5.", "design": "This is an interventional study with 21 participants. Participants will be randomly assigned to receive one of three doses of Arginine Hydrochloride.", "commitments": "You would receive Arginine Hydrochloride infusions three times a day for up to five days, or until hospital discharge. Mitochondrial function will be measured at the start of the study and on day 5.", "compensation": "Not stated in the trial record.", "follow_up": "Mitochondrial function will be measured at baseline and on day 5.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Arginine Replacement Therapy in COVID-19
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Claudia R. Morris, MD · PRINCIPAL_INVESTIGATOR · Emory University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in mitochondrial functionBaseline and day 5
Complex-IV activity changes will be measured to estimate mitochondrial function before and after administration for L-arginine