Back to search results

ESP Block for Minimally Invasive Lumbar Spine Surgery

This study is looking at whether a nerve block called an erector spinae plane (ESP) block can help reduce the need for opioid pain medications after minimally invasive lumbar spine surgery (MIS TLIF). The ESP block uses bupivacaine and dexamethasone to help with pain. Researchers want to see if patients who receive the ESP block use less opioid pain medication in the 24 hours after surgery compared to those who don't. You might be able to join if you are between 18 and 80 years old, are having MIS TLIF surgery, and meet certain health criteria. The current recruitment status is unclear.

Study design
This is a randomized controlled trial with 48 participants. Patients will be randomly assigned to receive either the ESP block or no ESP block.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, opioid use, is measured at 24 hours postoperatively.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05856539

ESP Block in MIS Lumbar Spine Surgery

Recruiting
NAAges 18–80InterventionalTreatment
Hospital for Special Surgery, New York
~48 participants
Updated 2025-10-06 on ClinicalTrials.gov
What's tested:Erector spinae plane (ESP) block

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
24-hour oral morphine milligram equivalents (OMEs)
Measured over 24 hours postoperatively

Conditions

Patients With Spinal Stenosis Indicated for MIS TLIF

Explore related trials

Spinal Stenosis

Where it's being run

1 sites across 1 states
New York1

Who to contact

Sheeraz Qureshi, MD, MBA
[email protected]
919-260-9699
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age 18-80
Patients scheduled for MIS TLIF (any level) with the principal investigator
ASA 1, 2, 3

Exclusion

ASA 4 or higher
BMI \>40
Chronic opioid use (daily use for \> 3 months)
Revision surgery, any history of previous lumbar spine surgery
Allergy to any of the study medications
Non-English speaking
Chronic renal insufficiency or failure (creatinine \>2) or severe hepatic disease (cirrhosis, failure)
Pregnancy
Any concomitant surgery

What this trial measures

  • 24-hour oral morphine milligram equivalents (OMEs)24 hours postoperatively

    The primary outcome of the study will be cumulative opioid use in the first 24 hours postoperatively in oral morphine milligram equivalents (OMEs) (24 hour period from PACU admission to POD1).