SMARTer Weight Loss Management for Obesity

This study, called SMARTer Weight Loss Management, is looking at different ways to help people with obesity lose weight. It compares three approaches: the SMARTer intervention (using a smartphone app, online learning, and remote health sessions), the Diabetes Prevention Program (DPP) (using a logbook, guide, and remote sessions), and a Self-Guided Treatment (providing paper and internet resources). The study wants to see if the SMARTer intervention can help people lose a similar amount of weight as DPP, but at a lower cost. You might be able to join if you are over 18, have a BMI of 25 or higher (but weigh less than 396 lbs), own a smartphone, and are not currently in another weight loss program. The main goal is to measure the percentage of weight change and the difference in weight (in kilograms) after 6 months.

Study design
This is a randomized controlled study with three groups, planning to enroll 492 participants. Participants will be randomly assigned to one of the three intervention groups.
What's involved
You would have physical measurements taken at the start, 3 months, 6 months, 9 months, and 12 months. The active intervention phase lasts 24 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your weight loss will be evaluated at 3, 6, 9, and 12 months after the start of the study.

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NCT05861973

SMARTer Weight Loss Management

Recruiting
NAAges 18+InterventionalTreatment
Florida State University
~492 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:Adaptive SMARTer intervention (SMARTer)Diabetes Prevention Program (DPP)Self-Guided Treatment (Self-Guided)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Weight - percent change
Measured over Baseline to 6-months
+1 more outcome measured
Obesity
1 sites across 1 states
Florida1
  • Bonnie Spring, PhD · PRINCIPAL_INVESTIGATOR · Florida State University

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Eligibility criteria

Inclusion

Over 18 years old
BMI of ≥25, weight \<396 lbs
Must own a Smartphone, and be willing to install the SMARTer app
Not enrolled in a formal weight loss program

Exclusion

Cerebrovascular accident or myocardial infarction within six months of enrollment
Diabetes treated with insulin
Pregnancy, lactation or intended pregnancy
Active suicidal ideation
Anorexia or bulimia
Requiring an assistive device for mobility
Taking weight loss medications, such as GLP-1 agonists
  • Weight - percent changeBaseline to 6-months

    Participant percent change in weight (kg) from baseline to 6-months.

  • Weight - difference in kgBaseline to 6-months

    Participant change in weight (kg) from baseline to 6-months.