Can Food Timing Reduce Your Diabetes Risk?
This study is looking at how the timing of your meals might affect your body's metabolism, specifically related to diabetes risk. Researchers want to see if eating at different times, without changing what you eat overall, impacts how your body handles sugar (glucose tolerance) and fats (plasma triglyceride levels), and how much energy your body burns after eating (diet-induced thermogenesis). You might be assigned to a day shift or simulated night shift schedule, and different meal timing plans (Diet order A-B or B-A). The study is for healthy individuals aged 18 to 45 with a BMI between 18.5 and 29.9. Smokers, pregnant individuals, and those with drug or alcohol dependency cannot participate. The study plans to enroll 48 participants.
- Study design
- This interventional study plans to enroll 48 participants. It will compare different meal timing protocols under simulated day and night shift conditions.
- What's involved
- You would complete two inpatient stays, be provided with test meals, and have frequent blood draws.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcomes are measured at 24 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Can Food Timing Reduce Your Diabetes Risk?
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Frank Scheer, PhD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Difference in glucose tolerance between Meal Conditions and Shift Work24 hours
Glucose incremental area under the curve (AUC) from mixed meal tests
- Difference in diet-induced thermogenesis between Meal Conditions and Shift Work24 hours
Postprandial energy expenditure incremental area under the curve (AUC) from mixed meal tests
- Difference in plasma triglyceride level between Meal Conditions and Shift Work24 hours
Triglyceride area under the curve (AUC) over 24 hours