Cognitive Training for Gynecologic Cancer Patients Undergoing Chemotherapy

This study is looking at whether using a cognitive training application on a smartphone or tablet can help reduce "chemobrain" (cancer-related cognitive impairment) in women with gynecologic cancer who are receiving chemotherapy. Chemobrain can cause difficulties with memory and clear thinking. The study will involve patients using this application and taking tests to measure their thinking abilities during and after chemotherapy. The goal is to see if this training can improve or prevent these cognitive difficulties. You may be able to join if you are a woman between 18 and 90 years old, have a newly diagnosed gynecologic cancer, are undergoing chemotherapy, and own a smartphone or tablet. The study aims to enroll 64 participants, but its current status is unclear.

Study design
This is an interventional study planning to enroll 64 women. It will test the effects of a cognitive training application.
What's involved
You would use a cognitive training application and undergo neurocognitive testing during and after chemotherapy.
Compensation
Not stated in the trial record.
Follow-up
Your neurocognitive function will be measured from the start of chemotherapy through 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05864274

Improve Cancer-related Cognitive Impairment

Recruiting
NAAges 18–90InterventionalHealth services
University of Alabama at Birmingham
~64 participants
Updated 2025-11-24 on ClinicalTrials.gov
What's tested:Cognitive training application

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Neurocognitive function
Measured over From initiation of chemotherapy through 2 years
+1 more outcome measured
Gynecologic Cancer
Chemotherapy Effect
Chemo-brain
Cancer-related Cognitive Difficulties
1 sites across 1 states
Alabama1

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Eligibility criteria

Inclusion

newly diagnosed gynecologic malignancy (uterine, cervical, ovarian, primary peritoneal, vulvar, or vaginal) and undergoing chemotherapy
own a smartphone or tablet with ability to download cognitive training application
and age \>21 years old

Exclusion

medical diagnosis of dementia
significant underlying mental diagnoses for which they are on more than 1 medication for (patients with depression or anxiety on single-agent therapy will be able to participate
age \<21
  • Neurocognitive functionFrom initiation of chemotherapy through 2 years

    Evaluated by the NIH Toolbox of Assessment of Neurologic Behavioral Function

  • Neurocognitive functionFrom initiation of chemotherapy through 2 years

    Evaluated by the FACT-Cog survey