tDCS + CCFES for Post-stroke Upper Extremity Hemiplegia

This study is testing if different types of non-invasive brain stimulation, called transcranial direct current stimulation (tDCS), combined with therapy can help people regain hand movement after a stroke. The study compares three approaches: active conventional tDCS, active unconventional tDCS, and sham tDCS (a placebo version), all used with Contralaterally Controlled Functional Electrical Stimulation (CCFES) and occupational therapy. Researchers want to see which combination leads to the most improvement in hand movement, measured by how well participants can move blocks. You might be able to join if you are 21-90 years old, had a stroke 6-24 months ago, and can follow simple commands.

Study design
This is a randomized clinical trial with 63 participants. Participants, therapists, and assessors will not know which tDCS treatment is being received.
What's involved
The treatment will last 12 weeks. The study will assess your hand movement at 6, 12, 24, and 36 weeks.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after the 12-week treatment period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05866003

tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia

Recruiting
NAAges 21–90InterventionalTreatment
MetroHealth Medical Center
~63 participants
Updated 2025-09-29 on ClinicalTrials.gov
What's tested:Active conventional tDCS montage plus CCFESActive unconventional tDCS montage plus CCFESSham tDCS plus CCFESCCFES with Occupational Therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Box and Blocks Test (BBT)
Measured over Change in BBT will be assessed at 6 weeks, 12 weeks, 24 weeks, and 36 weeks
Stroke
Upper Extremity Paresis
Hemiplegia
1 sites across 1 states
Ohio1
  • David A Cunningham, PhD · PRINCIPAL_INVESTIGATOR · MetroHealth Medical Center and Case Western Reserve University

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  • Box and Blocks Test (BBT)Change in BBT will be assessed at 6 weeks, 12 weeks, 24 weeks, and 36 weeks

    The BBT counts how many blocks a patient can pick up, move over a barrier, and release in 60 seconds.