Study of ASKG915 for Advanced Solid Tumors

This study is looking at a new treatment called ASKG915 for people with advanced solid tumors (cancers that have spread). The study will test ASKG915 by itself and in combination with standard treatments like Paclitaxel + Bevacizumab, Fruquintinib, or Docetaxel. Researchers want to understand how safe ASKG915 is, how well your body handles it, and how it affects your cancer. To join, you must have a cancer that hasn't responded to other treatments or for which there are no standard treatments available, be at least 18 years old, and have a good enough general health status. The main goals are to identify any serious side effects and other adverse events (unwanted effects) that might occur.

Study design
This is an interventional study with a planned enrollment of 594 participants. It involves different parts to test ASKG915 alone and in combination with other standard treatments.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Adverse events will be measured from the first dose to 30 days after the last dose.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05867420

A Study of ASKG915 in Patients With Selected Advanced Solid Tumors.

Recruiting
PHASE1Ages 18+InterventionalTreatment
AskGene Pharma, Inc.
~594 participants
Updated 2026-01-27 on ClinicalTrials.gov
What's tested:ASKG915Paclitaxel + BevacizumabFruquintinibDocetaxel

At a glance

Recruiting sites
3 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Dose limiting toxicities (DLTs)
Measured over 21days or 28 days
+1 more outcome measured
Advanced Solid Tumors

NCT05867420

Where you'd take part

This study runs at 4 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, Chinastudy coordinator listed

    Recruiting

  • Peking University Cancer Hospital

    Beijing, Beijing Municipality, Chinastudy coordinator listed

    Not yet recruiting

  • Columbia University Irving Medical Center

    New York, New Yorkno site contact published

    Recruiting

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvaniano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Jing Chen, MD · STUDY_DIRECTOR · Ask-Gene Pharma, Inc.

Opens a ready-to-send draft in your own email app — review before sending.

  • Dose limiting toxicities (DLTs)21days or 28 days

    To evaluate the safery of ASKG915 in subjects.

  • Adverse events(AEs)From the first dose to 30 days after the last dose

    To evaluate the safery of ASKG915 in subjects.