This study is investigating if high doses of intravenous human albumin (1g/kg, with a minimum of 50g and maximum of 100g) can help patients with refractory ascites. Refractory ascites is a condition where fluid builds up in the abdomen due to advanced liver cirrhosis, even after trying strong diuretic medications. The goal is to see if regular albumin infusions can reduce how often patients need large volume paracentesis (a procedure to remove fluid from the abdomen) and the total amount of fluid removed over one year. The study aims to enroll 100 participants who are at least 18 years old and have liver cirrhosis with refractory ascites.

Study design

This is a prospective, parallel, randomized, open-label clinical trial. It plans to enroll 100 participants with advanced cirrhosis.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for one year to measure the number of paracentesis procedures and the volume of fluid removed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.