This study is comparing two ways to help infants breathe after heart surgery for congenital heart disease (CHD). After surgery, babies are often on a breathing machine (intubated) and then taken off (extubated). This study wants to find out if High Flow Nasal Cannula (HFNC) or Non-Invasive Positive Pressure Ventilation (NIPPV) is better at preventing breathing problems after extubation. Researchers will look at how well each method works to avoid needing the breathing tube again within two weeks after surgery. You might be able to join if you are an infant up to 1 year old or weighing up to 10 kg, admitted to the cardiac intensive care unit after heart surgery for CHD.

Study design

This study will involve 200 participants who will be randomly assigned to receive either High Flow Nasal Cannula or Non-Invasive Positive Pressure Ventilation.

What's involved

Participants will receive either High Flow Nasal Cannula or Non-Invasive Positive Pressure Ventilation following extubation, with clinical monitoring and respiratory support adjusted as needed.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome of avoiding extubation failures will be measured up to 2 weeks after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.