Preventing Postpartum Depression in Immigrant Latinas

This study is testing a virtual group program called "Mothers and Babies Virtual Group Intervention" (MBVG) to help prevent postpartum depression (PPD) in immigrant Latina mothers. PPD is a type of depression that can happen after childbirth. The MBVG program uses principles from cognitive-behavioral therapy (CBT), which helps you change unhelpful thinking patterns, and attachment theory, which focuses on the bond between a parent and child. You might be able to join if you are a Latina woman, at least 16 years old, speak Spanish, are pregnant or have a baby younger than 9 months, and have access to a device for virtual sessions. We are looking to see if this program can reduce depressive symptoms and new cases of depression, and improve how confident you feel as a parent.

Study design
This is an interventional study planning to enroll 300 participants. The study status is currently unclear.
What's involved
You would participate in 10 virtual sessions of the Mothers and Babies Virtual Group Intervention. Your depressive symptoms and parenting confidence would be measured at 3 and 6 months after the intervention.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after completing the intervention to assess depressive symptoms and parenting self-efficacy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05873569

Preventing Postpartum Depression in Immigrant Latinas

Active, Not Recruiting
NAAges 16+InterventionalPrevention
Northwestern University
~300 participants
Updated 2026-08-10 on ClinicalTrials.gov
What's tested:Mothers and Babies Virtual Group Intervention

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Depressive symptoms
Measured over We are examining change in depressive symptoms from baseline to 6-months post-intervention
+3 more outcomes measured
Postpartum Depression
1 sites across 1 states
Maryland1
  • Darius Tandon, PhD · PRINCIPAL_INVESTIGATOR · Northwestern University
  • Rheanna Platt, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Self-identify as Latina
Speak Spanish
Be at least 16 years old
Be pregnant or have a child \<9 months
Have access to a device they can use for MB-VG sessions.
Elevated depressive symptoms either scores of 5-14 on the Edinburgh Postnatal Depression Scale (EPDS) and/or scores 3.5 or greater prenatally or 4.5 or greater prenatally on the Postpartum Depression Predictors Inventory.

Exclusion

Individuals who score \>14 on the EPDS are exhibiting moderately severe to severe depressive symptoms and will be excluded given our prevention focus.
Individuals not at risk for PPD-i.e., EPDS scores \<5 and under the PDPI-R cutoff-will also be excluded.
  • Depressive symptomsWe are examining change in depressive symptoms from baseline to 6-months post-intervention

    Depressive symptoms will be measured using the Center for Epidemiologic Studies-Depression (CES-D) scale. The CES-D consists of 20 questions that map onto DSM criteria for depression, with higher scores indicating greater depressive symptoms. The range for the CES-D is 0-60.

  • Depressive episodesWe are examining new cases of depressive episodes at 3- and 6-months post-intervention

    Depressive episodes will be measured using the Mood Disorders module of the Structured Clinical Interview for DSM-V (SCID-5), a semi-structured interview for DSM-V Axis 1 diagnoses. The presence of a depressive episode is ascertained by scoring responses to the SCID questions, with major depression diagnosis ascribed to individuals who endorse: (a) 5 or more depressive symptoms for ≥ 2 weeks, (b) Must have either depressed mood or loss of interest/pleasure, (c) Symptoms must cause significant distress or impairment, and (d) No manic or hypomanic behavior.

  • Parenting self-efficacyWe will examine parenting self-efficacy at 3- and 6-months post-intervention

    Parenting self-efficacy will be measured using the self-efficacy subscale of the Parental Cognitions and Conduct Toward the Infant Scale (PACOTIS). The subscale has 7 items, with higher scores indicating greater parental self-efficacy. Calculate the mean score for each subscale. Scores range from 0-10.

  • Parenting responsivenessWe will examine parenting responsiveness at 3- and 6-months post-intervention

    Parenting responsiveness will be measured using the parental responsiveness subscale of the Parental Cognitions and Conduct Toward the Infant Scale (PACOTIS). The subscale has 7 items, with higher scores indicating greater parental responsiveness. Calculate the mean score for each subscale. Scores range from 0-10.