NCT05876910

Neural Mechanisms for Stopping Ongoing Speech Production

Enrolling by Invitation
NAAges 18–65InterventionalBasic science
University of California, San Francisco
~30 participants
Updated 2024-10-08 on ClinicalTrials.gov
What's tested:Speech Production Tasks

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Mean Change in Neural Activity
Measured over During inpatient hospitalization, up to 14 days after surgical electrode implantation
Epilepsy
Speech
1 sites across 1 states
California1
  • Lingyun Zhao, PhD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
  • Edward F Chang, MD · STUDY_CHAIR · University of California, San Francisco

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Participants with medication refractory epilepsy at UCSF undergoing surgical electrode implantation of subdural electrode arrays to define their seizure focus and
Participants with electrodes implanted who are willing and able to cooperate with study tasks.

Exclusion

Participants who lack capacity,
Participants who decline to provide informed consent or
Participants with cognitive deficits that preclude reliable completion of study tasks.
  • Mean Change in Neural ActivityDuring inpatient hospitalization, up to 14 days after surgical electrode implantation

    The mean change in neural activity is calculated as the average change in neural activity across trials between a time period (\~1 second) after the visual cue and a time period (\~1 second) before the visual cue. Included neural activity is within the 30-minute period of cue viewing and speech production tasks.