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NCT05878015

A Study of Intravenous Acetaminophen for Small Bowel Obstruction

Enrolling by Invitation
PHASE4Ages 18+InterventionalSupportive care
Mayo Clinic
~18 participants
Updated 2026-05-12 on ClinicalTrials.gov
What's tested:Acetaminophen

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Resolution of small bowel obstruction
Measured over 3 days
+2 more outcomes measured

Conditions

Small Bowel Obstruction

Explore related trials

Small Intestinal Obstruction

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Tatjana Gavrancic, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Small bowel obstruction diagnosed by radiographic study; and
Abdominal pain on admission.
Nothing per mouth diet.
The ability to give appropriate consent or have an appropriate representative available to do so.

Exclusion

Known liver failure or cirrhosis.
Acetaminophen toxicity on admission.
Known acetaminophen allergy.
Alcohol intoxication on admission.
History of substance abuse.
Creatinine clearance \< 30 (or Creatinine level \> 2).
Liver transplant recipients.
Ileus on admission.
Admitted for surgical intervention for SBO.
Admitted for venting Gastric tube placement.
On chronic opioid therapy (defined as use of opioid on daily or near daily basis within previous 45 days (both long acting and short acting).
Presentation without abdominal pain on admission.
Already hospitalized for other reasons and develop SBO while at the hospital.
Pregnant women.
Unable to provide informed consent.

What this trial measures

  • Resolution of small bowel obstruction3 days

    Days until small bowel obstruction resolution, measured by admission date to date that diet was placed

  • Pain Scores3 days

    Pain is measured by a pain scale of subjective pain reported by patients and measured by nurses and ranges from 0 (no pain) to 10 (worst pain).

  • Length of hospital stay3 days

    Measured by days from admission day to discharge day