Re-Evaluating Suicidal Thoughts (REST) for Veterans

This study is testing a new, brief, web-based program called "Re-Evaluating Suicidal Thoughts" (REST) to help Veterans who are experiencing suicidal thoughts. REST aims to teach coping skills to ease emotional distress and correct common misunderstandings about suicidal thoughts. Researchers want to see if Veterans using REST show more improvement in their suicidal thoughts and behaviors compared to those receiving their usual mental health care. You might be able to join if you are a Veteran, 18 or older, and have had suicidal thoughts in the past two weeks. The study will measure changes in suicidal thoughts and behaviors, and how flexible your thinking is about these thoughts.

Study design
This is an interventional study with 180 planned participants. It compares a new behavioral intervention (REST) to standard mental health care.
What's involved
Participants will either complete the REST intervention, which takes less than one hour, or continue with their usual mental health care. Suicidal ideation, psychological inflexibility, and suicidal behaviors will be measured at baseline, two weeks, and one month.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in suicidal ideation and behaviors for one month, and for changes in psychological inflexibility for two weeks.

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NCT05884476

Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans

Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~180 participants
Updated 2025-12-18 on ClinicalTrials.gov
What's tested:Treatment-as-usualRe-Evaluating Suicidal Thoughts

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Suicidal ideation severity change
Measured over Baseline and one month
+2 more outcomes measured
Suicidal Ideation
Suicide, Attempted
1 sites across 1 states
Louisiana1
  • Joseph W Boffa, PhD · PRINCIPAL_INVESTIGATOR · Southeast Louisiana Veterans Health Care System, New Orleans, LA

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Eligibility criteria

Inclusion

Veteran
18 years or older
Past two-week suicidal ideation as indicated by positive reply to C-SSRS questions ("Have you had any actual thoughts of killing yourself," or, "Have you been thinking about how you might do this?")

Exclusion

Active psychosis
Unmedicated bipolar disorder
Instances in which a substance use disorder would indicate inpatient detoxification prior to engaging in other outpatient mental health interventions
  • Suicidal ideation severity changeBaseline and one month

    Data sourced from Beck Scale for Suicidal Ideation (BSS) self-report measure total score. BSS scores range from 0-38 on 19 items rated on a 0-2 scale. Higher scores indicate greater suicidal ideation severity.

  • Psychological inflexibility of suicidal ideation changeBaseline and two weeks

    Data sourced from Acceptance and Action Questionnaire for Suicidal Ideation (AAQ-SI) self-report measure total scores. AAQ-SI scores range from 4-28 on seven items rated on a 1-7 scale. Higher scores indicate greater experiential avoidance of suicidal ideation.

  • Suicidal behaviors changeBaseline and one month

    Data sourced from the Columbia Suicide Severity Rating Scale clinical interview (C-SSRS). The presence or absence of five categories of suicidal behaviors is indicated on a dichotomous (Yes/No) scale. Categories include: (1) Preparatory acts or behavior, (2) aborted attempt, (3) interrupted attempt, (4) actual attempt (non-fatal), and (5) completed suicide. Higher assigned score indicates greater severity of suicidal behavior.