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Fat Flap Reconstruction for Neck Injury After Cancer Treatment

This study is looking at whether a procedure called the fat ALT flap can safely and effectively reduce neck problems (morbidity) for people with Head and Neck Squamous Cell Carcinoma (HNSCC) after they've had radiation and surgery. Neck problems can include difficulty swallowing, pain, stiffness, swelling, or changes to how the neck looks. Researchers want to see if this procedure improves your quality of life, which they will measure using questionnaires. You might be able to join if you are 18 or older, have HNSCC, are having radiation with or without chemotherapy, and then need a salvage neck dissection where additional flap coverage is recommended. The study plans to enroll 12 participants, but its current status is unclear.

Study design
This interventional study aims to enroll 12 participants. It is not specified if it is randomized or blinded.
What's involved
You will complete questionnaires like Face Q, Neck Dissection Impairment Index, and LENT-SOMA. Objective quality-of-life measures will be recorded at 12 months postoperatively.
Compensation
Not stated in the trial record.
Follow-up
Complications will be measured within 90 days post-operatively. Objective quality-of-life measures will be recorded at 12 months postoperatively.

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NCT05889091

A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

Recruiting
NAAges 18+InterventionalTreatment
Memorial Sloan Kettering Cancer Center
~12 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:HRQOL instrumentsLENT SOMA instrument

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of patients that experience a complications
Measured over within 90 days post operatively

Conditions

Head and Neck Squamous Cell Carcinoma

Explore related trials

Head and Neck Squamous Cell Carcinoma

Where it's being run

1 sites across 1 states
New York1

Study leadership

  • Evan Matros, MD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

Who to contact

Evan Matros, MD
[email protected]
646-608-8044
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients 18 years or older
Diagnosed with HNSCC (e.g., oropharyngeal, hypo/laryngeal SCC)
Primary treatment is with radiotherapy with or without chemotherapy
Salvage neck dissection is subsequently indicated for persistent or recurrent, nonmucosal disease in cervical lymph nodes
At the time of salvage neck dissection additional flap coverage is indicated to improve carotid coverage or replace missing skin

Exclusion

Patients with primary site mucosal recurrence in addition to neck disease

What this trial measures

  • Proportion of patients that experience a complicationswithin 90 days post operatively

    Flap-related surgical complications - subjective and objective outcomes using validated instruments and CTCAE V5.0 i. Partial/total flap loss ii. Venous/arterial thrombosis iii. Infection iv. Hematoma v. Seroma Donor site i. Hematoma ii. Infection iii. Seroma iv. Dehiscence