EMPOWER: Weight Loss and Exercise Post-stroke

This study, called EMPOWER, is looking at how a Lifestyle Management Program and POWER training (Post-stroke Optimization of Walking using Explosive Resistance) can help people who have had a stroke and are also overweight or obese. The Lifestyle Management Program uses dietitians, exercise physiologists, and psychologists to help with weight loss. POWER training involves 12 weeks of exercises like leg presses and jump training to improve walking. The study wants to see if these interventions improve physical function after 15 weeks. You might be able to join if you are 35-85 years old, had a stroke at least 6 months ago, have some weakness in your leg, can walk without help, and have a body mass index (BMI) greater than 25. The current status of this study is unclear.

Study design
This is an interventional study with a planned enrollment of 130 participants.
What's involved
Participants in the POWER training group will have 3 sessions per week for 12 weeks. The Lifestyle Management Program involves a structured dietary intervention.
Compensation
Not stated in the trial record.
Follow-up
Physical function will be measured at 15 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05901675

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

Recruiting
NAAges 35–85InterventionalHealth services
Medical University of South Carolina
~130 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:Lifestyle Management ProgramPost-stroke Optimization of Walking using Explosive Resistance

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Physical Function
Measured over 15 weeks
Obesity
Stroke
1 sites across 1 states
South Carolina1
  • Chris Gregory, PhD, PT · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

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  • Physical Function15 weeks

    Participating in a lifestyle management program (DIET or DIET+Ex) will improve performance on the six-minute walk test (6MWT) compared to those in the waitlist control and DIET groups.