Radiofrequency Ablation for Benign Thyroid Nodules in LatinX Patients

This study is investigating a non-surgical treatment called radiofrequency ablation (RFA) using the Mygen V-1000 RF system for LatinX patients who have benign (non-cancerous) thyroid nodules that are causing symptoms like cosmetic concerns, pressure, or hormone issues. RFA uses heat to shrink the nodule and avoids the risks of surgery. The study aims to see if this procedure is a safe and effective alternative to surgery for this specific patient group. To join, you must be 18 to 90 years old, identify as LatinX, and have a benign, symptomatic thyroid nodule that meets certain ultrasound criteria. The study will measure how much the thyroid nodule shrinks over 2 years to determine if the treatment is successful. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 44 participants. The phase of the study is not specified.
What's involved
If you join, you will complete questionnaires, have blood tests, undergo thyroid ultrasounds, and receive the radiofrequency ablation treatment. You will be followed for 2 years.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 2 years after treatment to measure changes in thyroid nodule volumes.

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NCT05903196

Radiofrequency Ablation Study in LatinX Patients

Recruiting
NAAges 18–90InterventionalDiagnostic
Northwell Health
~44 participants
Updated 2025-09-23 on ClinicalTrials.gov
What's tested:Mygen V-1000 RF system

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with treatment-related changes in thyroid nodule volumes
Measured over 2 years
Thyroid Nodule
1 sites across 1 states
New York1
  • Daniel Kuriloff, MD · PRINCIPAL_INVESTIGATOR · Northwell Health

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Eligibility criteria

Inclusion

Subject capable of giving informed consent
Stated willingness to comply with all study procedures and availability for the duration of the study
Subjects over 18 years of age
Subject who self-identifies as LatinX
Subjects who have a benign, symptomatic thyroid nodule
Subjects whose nodule has well-defined margin on ultrasound and is surrounded by at least 2mm of normal thyroid parenchyma in all directions

Exclusion

Patients who are pregnant, trying to become pregnant, or breastfeeding
Patient who have a cardiac pacemaker,defibrillator , or other electromedical equipment
Patients who have a nodule that is malignant or not predominantly solid (must be \>50% solid by ultrasound)
Patients who cannot give consent
Patients on anticoagulation or dual antiplatelet therapy
Patients with acute illness
People with BP \> 140/90 prior to the scheduled procedure
  • Number of participants with treatment-related changes in thyroid nodule volumes2 years

    To study the change in nodule volume