Observational Study on Stroke Treatment for Patients with Existing Disability

This study, called TESTED, is looking at how well two different treatments work for people who have had a stroke (acute ischemic stroke) and already have some disability. It compares Endovascular Stroke Treatment (a procedure to remove blood clots from the brain) with Medical Management (which can include medications like intravenous thrombolysis, antiplatelets, and blood pressure drugs, plus rehabilitation). You might be able to join if you are an adult, have a moderate to severe disability before your stroke, and arrive at the hospital within 24 hours of your stroke symptoms starting. The main goal is to see how your functional ability changes 90 days after treatment. The study is currently unclear on its recruitment status.

Study design
This is an observational study, meaning researchers will look at existing medical care rather than assigning treatments. It aims to include 1060 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your functional ability will be checked about 90 days after your treatment starts.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05911568

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

Recruiting
Not specifiedAges 18+Observational
University of Cincinnati
~1,060 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:Endovascular Stroke TreatmentMedical Management

At a glance

Recruiting sites
25 of 25 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
modified Rankin Scale (mRS)
Measured over 90 (±14) days after treatment initiation
Stroke
Stroke, Acute
Stroke, Ischemic
25 sites across 18 states
California4
New York3
Connecticut2
Tennessee2
Arizona1
Colorado1
Florida1
Georgia1
  • Eva Mistry, MD · PRINCIPAL_INVESTIGATOR · University of Cincinnati
  • Jeffrey Saver, MD · PRINCIPAL_INVESTIGATOR · Ronald Reagan UCLA Medical Center
  • J Mocco, MD · PRINCIPAL_INVESTIGATOR · Icahn School of Medicine at Mount Sinai
  • Heidi Sucharew, PhD · PRINCIPAL_INVESTIGATOR · University of Cincinnati

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  • modified Rankin Scale (mRS)90 (±14) days after treatment initiation

    Score of 0-3, 4, 5 or 6 on the modified Rankin Scale (mRS) (Note: mRS range: 0 (no residual symptoms) to 6 (death)