Observational Study on Stroke Treatment for Patients with Existing Disability
This study, called TESTED, is looking at how well two different treatments work for people who have had a stroke (acute ischemic stroke) and already have some disability. It compares Endovascular Stroke Treatment (a procedure to remove blood clots from the brain) with Medical Management (which can include medications like intravenous thrombolysis, antiplatelets, and blood pressure drugs, plus rehabilitation). You might be able to join if you are an adult, have a moderate to severe disability before your stroke, and arrive at the hospital within 24 hours of your stroke symptoms starting. The main goal is to see how your functional ability changes 90 days after treatment. The study is currently unclear on its recruitment status.
- Study design
- This is an observational study, meaning researchers will look at existing medical care rather than assigning treatments. It aims to include 1060 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your functional ability will be checked about 90 days after your treatment starts.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
At a glance
Conditions
Where it's being run
25 sites across 18 statesStudy leadership
- Eva Mistry, MD · PRINCIPAL_INVESTIGATOR · University of Cincinnati
- Jeffrey Saver, MD · PRINCIPAL_INVESTIGATOR · Ronald Reagan UCLA Medical Center
- J Mocco, MD · PRINCIPAL_INVESTIGATOR · Icahn School of Medicine at Mount Sinai
- Heidi Sucharew, PhD · PRINCIPAL_INVESTIGATOR · University of Cincinnati
Who to contact
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What this trial measures
- modified Rankin Scale (mRS)90 (±14) days after treatment initiation
Score of 0-3, 4, 5 or 6 on the modified Rankin Scale (mRS) (Note: mRS range: 0 (no residual symptoms) to 6 (death)