Informational and Supportive Care for Rectal Cancer (PATHWAYS)

This study is testing an informational and supportive care program called PATHWAYS for people with locally advanced rectal cancer (LARC). PATHWAYS involves four coaching sessions and a patient education guidebook. It's being compared to an "enhanced usual care" group, which receives an information resource guide. The main goal is to see if it's practical and acceptable to conduct a larger study on PATHWAYS. You might be able to join if you are at least 18 years old, have newly diagnosed LARC (stage II or III), and are starting multi-modality treatment (like chemotherapy and radiation). About 80 people are expected to participate in this study.

Study design
This is a randomized controlled trial, meaning participants are randomly assigned to either the PATHWAYS intervention or enhanced usual care. It is a pilot study, with about 80 participants planned.
What's involved
Participants in the PATHWAYS group will have 4 coaching sessions. The study will measure how many participants stay in the intervention for 4 weeks.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint for feasibility is measured at 4 weeks.

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NCT05914766

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

Recruiting
NAAges 18+InterventionalSupportive care
Massachusetts General Hospital
~80 participants
Updated 2025-05-18 on ClinicalTrials.gov
What's tested:PATHWAYSEnhanced usual care

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of participants retained in the intervention (feasibility)
Measured over 4 weeks
Rectal Cancer
Self Efficacy
2 sites across 1 states
Massachusetts2
  • Kelsey Lau-Min, MD, MSCE · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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  • Proportion of participants retained in the intervention (feasibility)4 weeks

    The primary outcome will be feasibility, defined as ≥60% retention of participants over the four-week intervention.