[18F]FES PET/CT in Uterine Cancer

This study is looking at how well a special imaging scan, called [18F]FES PET/CT, can find estrogen receptor (ER) activity in uterine cancer. This scan uses a small amount of a radioactive tracer ([18F]fluoroestradiol) to highlight areas where cancer cells might be growing. You might be able to join if you are a woman at least 18 years old with uterine cancer that has come back, spread, or hasn't been treated with surgery, and has been confirmed by a biopsy or other scans. The study aims to see how often this scan shows positive results for ER+ (estrogen receptor positive) uterine cancer after one year. The study plans to enroll up to 30 participants, but its current recruitment status is unclear.

Study design
This is a Phase II interventional study, meaning it tests a specific intervention in a small group of people. It plans to enroll up to 30 women.
What's involved
If you join, you will have an [18F]FES PET/CT scan. This scan will happen before you start any new cancer treatment.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of the study, FES positivity, is measured at 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05916196

[18F]FES PET/.CT in Uterine Cancer

Recruiting
PHASE2Ages 18+InterventionalDiagnostic
Abramson Cancer Center at Penn Medicine
~30 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:18F-Fluoroestradiol

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
rate of FES positivity in ER+ uterine cancer
Measured over 1 year
Uterine Cancer
1 sites across 1 states
Pennsylvania1
  • Neil Taunk, MD · PRINCIPAL_INVESTIGATOR · Abramson CC

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  • rate of FES positivity in ER+ uterine cancer1 year

    Evaluate utility of FES PET/CT to detect estrogen receptor (ER+) uterine cancer lesions in patients with recurrent or metastatic uterine cancer