TMS-fNIRS for Post Traumatic Stress Disorder and Traumatic Brain Injury
This study is testing a new way to personalize Transcranial Magnetic Stimulation (TMS) treatment for people with Post Traumatic Stress Disorder (PTSD), with or without a mild Traumatic Brain Injury (TBI). TMS is a non-invasive (no surgery) brain stimulation technology. The study uses a brain imaging technology called functional Near Infrared Spectroscopy (fNIRS) to directly measure brain activity. This new method aims to improve how TMS is dosed, potentially making the treatment more effective. To join, you must be 18-70 years old, have a PTSD diagnosis, and be eligible for TMS treatment. The study will look at how TMS changes brain activity, as measured by fNIRS, over 3 to 33 months.
- Study design
- This is an interventional study planning to enroll 60 participants. It is testing a new way to guide TMS treatment using fNIRS technology.
- What's involved
- You would need to have a stable medication and therapy regimen for at least one month before starting the study and maintain it throughout.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will measure brain changes from 3 to 33 months after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
TMS-fNIRS Personalized Dosing
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Frank A Kozel, M.D., M.S.C.R., D.F.A.P.A. · PRINCIPAL_INVESTIGATOR · Florida State University
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- TMS induced Brain changes as measured by functional Near Infrared Spectroscopy (fNIRS) comparing Motor Cortex (MC) and Dorsolateral Prefrontal Cortex (dl-PFC)Months 3-33
The magnitude of brain activation based on fNIRS signal for the respective cortices at the individual level will be assessed and compared for the MC and dl-PFC.